Anti-Mouse IFNβ – Purified

Pricing & Details

Product No.I-440
Clone
MIB-5E9.1
Protein
IFNβ
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Interferon Beta
Isotype
Armenian Hamster
IgG
Applications
N
,
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
I-440-50 µg
50 µg
$71.00
In stock
Max:
Min: 1
Step: 1
I-440-500 µg
500 µg
$214.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Data

Antibody Details

Product Details

Reactivity Species
Mouse
Host Species
Armenian Hamster
Product Concentration
0.5 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day Ambient
Applications and Recommended Usage?
Quality Tested by Leinco
WB The purified antibody is recommended for Western blotting. The suggested concentration for this MIB-5E9.1 antibody for use in western blotting is 1-10 μg/ml.
Other Applications Reported In Literature ?
N This antibody is recommended for neutralization of mouse IFN-β bioactivity
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Armenian Hamster Anti-Mouse IFNβ (Clone MIB-5E9.1) recognizes Mouse IFNβ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-α proteins and a single IFN-ß protein. The second class, type II IFN, consists of a single protein, IFN-γ. IFN-α and IFN-ß signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN-ß has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-ß’s therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.

Antigen Details

Protein
PubMed
Research Area
Apoptosis
.
Cell Biology
.
Cell Death
.
Signal Transduction
.
Tumor Suppressors
General Western Blot Protocol

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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