Anti-Mouse Ts H-2^s,f – Alexa Fluor® 488

Purified Recombinant Mouse Ts H-2^s,f (>98%)

This Alexa Fluor® 488 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Alexa Fluor® is a trademark of Life Technologies Corporation.

Liquid

This Alexa Fluor® 488 conjugate is stable when stored at 2-8°C. Do not freeze.

Research Use Only

2-8°C Wet Ice

Blue Laser (488 nm) Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.

Mouse Anti-Mouse Ts H-2^s,f (Clone A4B2-Ky15) recognizes an epitope on Mouse Ts H-2^s,f. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

The H-2 complex represents the major histocompatibility complex (MHC) in mice (Mus musculus), encoding class I, class II, and class III gene products that play a critical role in immune recognition, antigen presentation, and immune regulation. Monoclonal antibody clone A4B2-Ky15 specifically targets antigenic determinants associated with T suppressor factor / H-2 complexes expressed on distinct subpopulation subsets of suppressor T cells carrying the H-2s or H-2f haplotypes. Antibodies against these specific MHC haplotypes serve as key analytical tools in cellular immunology for identifying suppressor T-cell pathways, investigating MHC restriction, and evaluating immune cell subset dynamics in transgenic or haplotype-defined murine models.

Found in Ts cells.

1. Hauptfeld, V. et al. (1985) Immunogenetics 21:193
2. Kapp, J. A. et al. (1980) J. Exp. Med. 152:235