Anti-Prolylcarboxypeptidase (PRCP) (13920)
Data
Immunohistochemistry:Detection of PRCP in paraffin-embedded human
tonsil with #13920 diluted 1:20
Immunoblotting: Detection of PRCP in (1) Jurkat cell lysate and
(2) human fetal liver lysate with #13920 diluted
1:200. - -
- -
Antibody DetailsProduct DetailsReactivity Species Human Host Species Rabbit Immunogen Recombinant fusion protein corresponding to aa 46-317 of human PRCP. Product Concentration Lot Specific Formulation PBS, 0.05% sodium azide, 50% glycerol. State of Matter Liquid Product Preparation Purified by Protein A affinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -20°C. Country of Origin USA Shipping Next Day 2-8°C Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Polyclonal Antibody specific to PRCP (Angiotensinase C) Background Prolylcarboxypeptidase (PRCP) cleaves C-terminal amino acids linked to a proline if proline has a
protected amino group or is part of a peptide chain. As a lysosomal enzyme, it has a sharp acid
pH optimum with shorter substrates, but with longer peptides, some activity is retained at neutral
pH. PRCP is found in a variety of human cells, including white blood cells, fibroblasts, and
endothelial cells, and organs such as kidney and lung, and it is excreted in urine. Because
angiotensins II and III share a common C terminus (-pro-phe-OH), and are substrates for PRCP,
prolylcarboxypeptidase has also been referred to as angiotensinase C. Antigen DetailsReferences & CitationsTechnical Protocols |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
