Anti-Respiratory Syncytial Virus (RSV)

Anti-Respiratory Syncytial Virus (RSV)

Product No.: F655

- -
- -
Respiratory Syncytial Virus
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
RSV, Respiratory Syncytial Virus, Orthopneumovirus
Mouse IgG1

- -
- -
Select Product Size
- -
- -

Antibody Details

Product Details

Reactive Species
Respiratory Syncytial
Types A&B
Host Species
Product Concentration
100 μg/ml
>90% monomer by analytical SEC and SDS-Page
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Product Preparation
This monoclonal antibody is purified from ascites fluid or culture medium by protein A chromatography or sequential differential precipitations.
Storage and Handling
This product contains no stabilizing proteins and should be stored at 2-8°C until ready to use. This clone is non-reactive with: Influenza A & B, Adenovirus, Para 1-3, Measles, Mumps
Country of Origin
Ships Overnight on Blue Ice
Applications and Recommended Usage?
Quality Tested by Leinco
ELISA This antibody is a good choice for a detection antibody in a sandwich ELISA
IF Recommended starting range 1:10-1:50
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.


Respiratory Syncytial Virus (Clone RSV-210915) is specific for the fusion protein of RSV Types A&B.
Respiratory syncytial virus (RSV) is a common respiratory virus that infects the majority of children by two years old1, 2. While usually mild, RSV can be serious in infants and older adults and is the leading cause of bronchiolitis and pneumonia in children less than one year of age in the United States1. A related pneumovirus, human metapneumovirus (hMPV), also significantly contributes to hospitalizations resulting from lower respiratory tract infection2. Antibodies have been described that bind and neutralize both RSV and hMPV fusion (F) proteins.

RSV F protein is a type I integral membrane protein that is synthesized as a 574 amino acid inactive precursor, assembled into a trimer, post-translationally modified, then cleaved to produce F1, F2, and intervening peptide pep273. Functional F protein has both pre- and post-fusion conformations. RSV F protein is highly conserved among RSV isolates from both A and B subgroups3 and is the primary target for antiviral drug development3 with several antigenic regions capable of introducing neutralizing antibodies2. RSV and hMPV F protein share ~36% sequence similarity.

Antigen Details

Research Area
Infectious Disease
Seasonal and Respiratory Infections

References & Citations

1. National Center for Immunization and Respiratory Diseases (NCIRD), Division of Viral Diseases, Link Text
2. Mousa JJ, Binshtein E, Human S, et al. PLoS Pathog. 14(2):e1006837. 2018.
3. McLellan JS, Ray WC, Peeples ME. Curr Top Microbiol Immunol. 372:83-104. 2013.
Indirect Elisa Protocol

Formats Available

- -
- -
Products are for research use only. Not for use in diagnostic or therapeutic procedures.