Anti-Tumor Endothelial Marker 5 Antibody (34028)

Product No.: 34028


Target Tumor Endothelial Marker 5 Product Type Polyclonal Applications IHC , IHC-P


Select Product Size 50 µg — $500.00	Qty Max: Min: 1 Step: 1 $500.00 ADD TO CART Login For mAb Advantage Pricing Contact Us for Bulk Quantities

Data

Immunohistochemistry:


Antibody Details Product Details Reactivity Species Human Host Species Rabbit Immunogen Synthetic peptide conjugated to KLH Product Concentration Lot Specific Formulation PBS containing 0.1% sodium azide State of Matter Liquid Product Preparation Purified by immunogen affinity chromatography Storage and Handling This antibody is stable at 4°C (short- term) and -70°C (long-term). Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunohistochemistry: Use at 10 ug/ml. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. Description Specificity Rabbit Polyclonal Antibody specific to Tumor Endothelial Marker 5 Background Tumor endothelial marker 5 (TEM5) is a member of the adhesion family of GPCRs and is upregulated in endothelial cells during tumor and physiologic angiogenesis. Soluble TEM5 (sTEM5) is shed by endothelial cells during angiogenesis and binds to glycosaminoglycans on extracellular matrix and cell surface proteoglycans. After proteolytic processing, an RGD- binding site for integrin alphavbeta3 is exposed on sTEM5. Adhesion of endothelial cells to immobilized proteolytically processed sTEM5 promotes their survival. Antigen Details NCBI Gene Bank ID TEM5 UniProt.org Q6YN44 Research Area Cancer Research References & Citations IHC-P

Antibody Details

Product Details

Reactivity Species

Human

Host Species

Rabbit

Immunogen

Synthetic peptide conjugated to KLH

Product Concentration

Lot Specific

Formulation

PBS containing 0.1% sodium azide

State of Matter

Liquid

Product Preparation

Purified by immunogen affinity chromatography

Storage and Handling

This antibody is stable at 4°C (short- term) and -70°C (long-term).

Country of Origin

USA

Shipping

Next Day 2-8°C

Applications and Recommended Usage?
Quality Tested by Leinco

Immunohistochemistry: Use at 10 ug/ml.

Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity

Rabbit Polyclonal Antibody specific to Tumor Endothelial Marker 5

Background

Tumor endothelial marker 5 (TEM5) is a member of the adhesion family of GPCRs and is upregulated in endothelial cells during tumor and physiologic angiogenesis. Soluble TEM5 (sTEM5) is shed by endothelial cells during angiogenesis and binds to glycosaminoglycans on extracellular matrix and cell surface proteoglycans. After proteolytic processing, an RGD- binding site for integrin alphavbeta3 is exposed on sTEM5. Adhesion of endothelial cells to immobilized proteolytically processed sTEM5 promotes their survival.