Anti-West Nile Virus, NS1 [Clone WNV-0206]
Anti-West Nile Virus, NS1 [Clone WNV-0206]
Product No.: W123
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Clone WNV-0206 Target NS1 West Nile virus Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Alternate Names NS1, Non-structural protein 1, WNV Isotype Mouse IgG1 κ Applications ELISA , Lateral Flow |
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Antibody DetailsProduct DetailsReactivity Species West Nile Host Species Mouse Immunogen Culture virus infected cell lysate; strain NY99 Product Concentration ≥1.0 mg/ml Purity >90% for SDS PAGE Formulation Formulated in 0.015 M phosphate buffered saline (0.85% NaCl), pH 7.2 and contains 0.05% sodium azide. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration. State of Matter Liquid Product Preparation This monoclonal antibody is purified by ion exchange chromatography. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2 – 8° C Wet Ice Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Anti-West Nile virus (Clone WNV-0206) is specific for WNV non-structural protein 1 (NS1). There is no cross-reactivity with other Flavivirus. Background West Nile Virus (WNV) is a mosquito-borne, enveloped, positive-stranded RNA
flavivirus1. Flavivirus nonstructural protein NS1 has been proposed as an antibody target
to avoid antibody-dependent enhancement2. NS1 is a 46-55 kDa glycoprotein that is
expressed as a dimer on the cell surface and as a soluble hexamer in the extracellular
space and in circulation during infection. WNV NS1 dimer consists of a ß-roll, wing, and
ß-ladder. Antigen DetailsResearch Area Category B Pathogens . Infectious Disease . Matched Pair . Viral . IVD Raw Material References & Citations1. Goo L, Debbink K, Kose N, et al. Nat Microbiol. 4(1):71-77. 2019. 2. Wessel AW, Doyle MP, Engdahl TB, et al. mBio. 12(5):e0244021. 2021. Technical Protocols Lateral Flow |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
