Recombinant Human Connective Tissue Growth Factor

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Pricing & Details

Product No.C727
Protein
Connective Tissue Growth Factor
Formats AvailableView All
Product Type
Recombinant Protein
Alternate Names
CCN2, Hypertrophic Chondrocyte-Specific Protein 24 [HCS24], IGFBP8, MGC102839, NOV2
Applications
ELISA
,
IF Microscopy
,
IP
Prod No.
Size
Price
Avail.
Qty
Add to cart
C727-20 µg
20 µg
$224.00
In stock
Max:
Min: 1
Step: 1
C727-100 µg
100 µg
$529.00
In stock
Max:
Min: 1
Step: 1
C727-500 µg
500 µg
$2,306.00
In stock
Max:
Min: 1
Step: 1
C727-1 mg
1 mg
$3,807.00
In stock
Max:
Min: 1
Step: 1

Antibody Details

Product Details

Reactivity Species
Human
Host Species
E. coli
Endotoxin Level
<1.0 EU/µg as determined by the LAL method
Purity
>98% by SDS-PAGE and HPLC
Storage and Handling
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Amino Acid Sequence
MGKKCIRTPK ISKPIKFELS GCTSMKTYRA KFCGVCTDGR CCTPHRTTTL PVEFKCPDGE VMKKNMMFIK TCACHYNCPG DNDIFESLYY RKMYGDMA
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Background
CTGF (connective tissue growth factor) is a cysteine-rich, matrix-associated, heparin-binding protein and a member of the CCN family of secreted cysteine rich regulatory proteins and is the major mitogenic and chemoattractant protein produced by umbilical vein and vascular endothelial cells. CTGF stimulates the proliferation and differentiation of chondrocytes, induces angiogenesis, promotes cell adhesion of fibroblasts, endothelial, and epithelial cells, and binds to IGF, TGF beta1, and BMP-4. Cell migration and adhesion are signaled through binding to specific cell surface integrins and to heparin sulfate proteoglycans CTGF, a lower molecular weight isoform containing the C-terminal portion of the full length CTGF protein, exerts full heparin binding, cell adhesion, and mitogenic CTGF activity.

Antigen Details

References & Citations

1. Fine, HA. et al. (2011) J Natl Cancer Inst. 103(15): 1162–1178.PubMed
Elisa Sandwich Protocol
Immunoprecipitation Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.