Desmoglein 1, also known as DSG1, is a human gene. Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. DGI expression may be a significant factor for invasion, metastasis, and prognosis of human esophageal cancer. 1
>95% by SDS-PAGE and analyzed by silver stain.
<1.0 EU/µg as determined by the LAL method
Data are not available currently.
Fusion Protein Tag
Fc Fusion Protein
Protein Accession No.
Amino Acid Sequence
whsirrqkre wikfaaacre gednskrnpi akihsdcaan qqvtyrisgv gidqppygif vinqktgein itsivdrevt pffiiycral nsmgqdlerp lelrvrvldi ndnppvfsma tfagqieens nantlvmiln atdadepnnl nskiafkiir qepsdspmfi inrntgeirt mnnfldreqy gqyalavrgs drdggadgms aececnikil dvndnipyme qssytieiqe ntlnsnllei rvidldeefs anwmaviffi sgnegnwfei emnertnvgi lkvvkpldye amqslqlsig vrnkaefhhs imsqyklkas aisvtvlnvi egpvfrpgsk tyvvtgnmgs ndkvgdfvat dldtgrpstt vryvmgnnpa dllavdsrtg kltlknkvtk eqynmlggky qgtilsiddn lqrtctgtin iniqsfgndd rtntepntki ttntgrqest sstnydtstt stdssqvyss epgngakdll sdnvhkscdk thtcppcpap ellggpsvfl fppkpkdtlm isrtpevtcv vvdvshedpe vkfnwyvdgv evhnaktkpr eeqynstyrv vsvltvlhqd wlngkeykck vsnkalpapi ektiskakgq prepqvytlp psrdeltknq vsltclvkgf ypsdiavewe sngqpennyk ttppvldsdg sfflyskltv dksrwqqgnv fscsvmheal hnhytqksls lspgk
N-terminal Sequence Analysis
State of Matter
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human Desmoglein-1 is Mr 82 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 110 kDa.
This recombinant protein was 0.2 µm filtered and lyophilized from a Tris, NaCl and Citrate, pH 6.5 solution.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
Next Day Ambient
NCBI Gene Bank
References & Citations
1. Shimada, M. et al. (1994) J Surg Oncol 57: 105-110.
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.