Recombinant Human Desmoglein-1

Desmoglein 1, also known as DSG1, is a human gene. Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily.
DGI expression may be a significant factor for invasion, metastasis, and prognosis of human esophageal cancer. ¹

Data are not available currently.

Fc Fusion Protein

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Glu50

Lyophilized

The predicted molecular weight of Recombinant Human Desmoglein-1 is Mr 82 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 110 kDa.

82

This recombinant protein was 0.2 µm filtered and lyophilized from a Tris, NaCl and Citrate, pH 6.5 solution.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Next Day Ambient

1. Shimada, M. et al. (1994) J Surg Oncol 57: 105-110.