Growth and Differentiation Factor 15 (GDF-15) is a member of the TGF-β Superfamily and also a member of the subfamily of Growth Differentiation Factors (GDFs) which play important roles in development. GDF-15 has a role in regulating inflammatory and apoptotic pathways during tissue injury and certain disease processes.
<0.1 EU/µg as determined by the LAL method
The biological activity of Human GDF-15-D was determined by the inhibition of DU-145 cells. The expected ED50= 1-2µg/ml.
Protein Accession No.
Amino Acid Sequence
MARNGDDCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLI QKTDTGVSLQ TYDDLLAKDC HCI
State of Matter
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human GDF-15-D is Mr 26.8 kDa.
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
Next Day Ambient
NCBI Gene Bank
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.