Recombinant Human GDF-15 – D-variant

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Pricing & Details

Product. No.G725
Alternate Names
Prostate Differentiation Factor, Placental TGF-beta, Macrophage Inhibitory Cytokine 1, MIC-1
Expression Host
E. coli
Species
Human
Prod No.
Size
Price
Avail.
Qty
Add to cart
G725-20 µg
20 µg
$224.00
In stock
Max:
Min: 1
Step: 1
G725-100 µg
100 µg
$581.00
In stock
Max:
Min: 1
Step: 1
G725-500 µg
500 µg
$2,524.00
In stock
Max:
Min: 1
Step: 1
G725-1 mg
1 mg
$4,163.00
In stock
Max:
Min: 1
Step: 1

Background

Growth and Differentiation Factor 15 (GDF-15) is a member of the TGF-β Superfamily and also a member of the subfamily of Growth Differentiation Factors (GDFs) which play important roles in development. GDF-15 has a role in regulating inflammatory and apoptotic pathways during tissue injury and certain disease processes.

Protein Details

Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human GDF-15-D was determined by the inhibition of DU-145 cells. The expected ED50= 1-2µg/ml.
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
MARNGDDCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLI QKTDTGVSLQ TYDDLLAKDC HCI
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human GDF-15-D is Mr 26.8 kDa.
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Description
G725
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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