Recombinant Human GITR Ligand

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Pricing & Details

Product. No.A214
Alternate Names
TNFSF18, GITRL, TL6
Expression Host
Sf 21 Insect Cells
Species
Human
Prod No.
Size
Price
Avail.
Qty
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A214-25 µg
25 µg
$369.00
In stock
Max:
Min: 1
Step: 1

Background

Activation-induced TNFR member ligand (AITRL) is a member of the TNF superfamily. It is expressed in endothelial cells and along with its receptor, AITR, seems to regulate interactions between endothelial cells and activated T lymphocytes. AITRL is a type II transmembrane protein containing 177 amino acid residues.

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human AITRL is determined by its ability to stimulate IL-8 production by human PBMC using a concentration range of 1.0-10.0 ng/ml. Results may vary with PBMC donors.
Fusion Protein Tag
Histidine Tag
Expression Host
Sf 21 Insect Cells
Protein Accession No.
Amino Acid Sequence
hhhhh hetakepcma kfgplpskwq masseppcvn kvsdwkleil qnglyliygq vapnanyndv apfevrlykn kdmiqtltnk skiqnvggty elhvgdtidl ifnsehqvlk nntywgiill anpqfis
N-terminal Sequence Analysis
His
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human AITRL is Mr 15 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 14-16 kDa.
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Description
A214
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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