Recombinant Human IFN-alpha 2a
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BackgroundInterferon-alpha 2a (IFNα 2a) is a Type I interferon made by leukocytes during viral infection. It has anti-viral and non-proliferative activity induced by JAK1-STAT signaling. IFN-alpha 2s are the most widely used type for therapeutic purposes. IFNα 2b is a variant of IFNα 2a that differs by one amino acid. Recombinant human IFNα 2a is a non-glycosylated protein, containing 166 amino acids, with a molecular weight of 19.37 kDa.
Protein DetailsPurity >98% by SDS-PAGE and HPLC Endotoxin Level <1.0 EU/µg as determined by the LAL method Biological Activity The activity is determined by the ability induce antiviral activity. Protein Accession No. Amino Acid Sequence MCDLPQTHSL GSRRTLMLLA QMRKISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET
LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE
SLRSKE
State of Matter Lyophilized Predicted Molecular Mass The molecular weight of Recombinant Human IFN alpha 2a is Mr 19.3 kDa. Storage and Stability The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein should be aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient NCBI Gene Bank IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
