Interferon-alpha 2b (IFNα 2b) is a Type I interferon made by leukocytes during viral infection. It has anti-viral and non-proliferative activity induced by JAK1-STAT signaling. IFN-alphas are the most widely used type for therapeutic purposes. IFNα 2b is a variant of IFNα 2a that differs by one amino acid. This recombinant human protein is a non-glycosylated protein, containing 166 amino acids, with a molecular weight of 19.4 kDa.
>98% by SDS-PAGE and HPLC
<1.0 EU/µg as determined by the LAL method
The biological activity of Human IFN-alpha 2b was determined in a viral CPE assay using EMC (Encephalomyocarditis) virus on A549 cells.
Protein Accession No.
Amino Acid Sequence
MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE
State of Matter
Predicted Molecular Mass
The molecular weight of Recombinant Human IFN-alpha 2b is Mr 19.4 kDa.
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. Avoid Repeated Freeze Thaw Cycles. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage.
Country of Origin
Next Day Ambient
NCBI Gene Bank
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.