Recombinant Human IL-16

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Pricing & Details

Product. No.I-197
Alternate Names
FLJ16806, HsT19289, Lymphocyte Chemoattractant Factor (LCF), PrIL-16
Expression Host
E. coli
Prod No.
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I-197-10 µg
10 µg
In stock
Min: 1
Step: 1
I-197-100 µg
100 µg
In stock
Min: 1
Step: 1
I-197-500 µg
500 µg
In stock
Min: 1
Step: 1
I-197-1 mg
1 mg
In stock
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.


Interleukin 16 (lymphocyte chemoattractant factor), also known as IL16, is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. IL-16 is released by a variety of cells (including lymphocytes and some epithelial cells) that has been characterized as a chemoattractant for certain immune cells expressing the cell surface molecule CD4. IL-16 has a critical role in protecting antigen presenting cells (APC) against HIV-1 infection and is used in the treatment of HIV disease.1

Protein Details

>95% by SDS-PAGE and HPLC
Endotoxin Level
<1.0 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human IL-16 (130 a.a.) has not been determined. The expected ED50 in a biological assay has not been determined. However, human IL-16 may be used as a standard in an ELISA assay to create a standard curve.
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
The DNA sequence encoding the putative 130 aa residue IL-16 monomer was inserted into a suitable expression vector and was expressed in E. coli (Cruikshank, W.W. et al., 1994, Proc. Natl. Acad. Sci. USA 91:5109 - 5113).
State of Matter
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human IL-16 is Mr 14 kDa.
This recombinant protein solution was 0.2 µm filtered and formulated in modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives present.
Storage and Stability
Working aliquots of this recombinant protein solution are stable for up to twelve months at -20°C to -70°C in a manual defrost freezer. Upon thawing, in the presence of a carrier protein, this recombinant protein can be stored at 2° - 8°C for one month without detectable loss of activity. For long-term storage, aliquot and freeze at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles.
Country of Origin
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Bahr GM. et al. (1999) J. Virol. 73: 7008
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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