Recombinant Human LIF

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Pricing & Details

Product. No.A323
Alternate Names
Leukocyte Inhibitory Factor
Expression Host
Insect Cells
Species
Human
Prod No.
Size
Price
Avail.
Qty
Add to cart
A323-25 µg
25 µg
$224.00
In stock
Max:
Min: 1
Step: 1
A323-100 µg
100 µg
$512.00
In stock
Max:
Min: 1
Step: 1
A323-500 µg
500 µg
$1,806.00
In stock
Max:
Min: 1
Step: 1
A323-1 mg
1 mg
$2,979.00
In stock
Max:
Min: 1
Step: 1

Background

Leukemia inhibitory factor (LIF) is a member of the interleukin 6 (IL-6) family that is made by a variety of adult and embryonic tissues. LIF signals through the glycoprotein 130 (gp130)/LIF receptor (LIFR) heterodimer to activate STAT3 and MAPK signaling. LIF functions during hematopoietic differentiation, neuronal cell differentiation, kidney development, and inflammatory processes. Human LIF may also be an important factor during human embryonic stem cell (hESC) self-renewal, pluripotency, and embryonic implantation.

Protein Details

Purity
>90% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Biological Activity
The biological activity was determined by the induction of endothelial cell sprouting as described in Korff et al., 2001.
Expression Host
Insect Cells
Protein Accession No.
Amino Acid Sequence
MSPLPITPVN ATCAIRHPCH NNLMNQIRSQ LAQLNGSANA LFILYYTAQG EPFPNNLDKL CGPNVTDFPP FHANGTEKAK LVELYRIVVY LGTSLGNITR DQKILNPSAL SLHSKLNATA DILRGLLSNV LCRLCSKYHV GHVDVTYGPD TSGKDVFQKK KLGCQLLGKY KQIIAVLAQA F
State of Matter
Lyophilized
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Description
L156
A323
Products are for research use only. Not for use in diagnostic or therapeutic procedures.