Recombinant Human Lymphotactin

Lymphotactin (LTN) is a chemokine produced mainly by activated CD8+ T-cells and directs migration of CD4+ and CD8+ lymphocytes and natural killer (NK) cells.¹ LTN plays an important role in maintaining the integrity of the epithelium and in mucosal immune responses.² Lymphotactin is a key regulator of lymphocyte motility and adhesion during acute allograft rejection.

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Lyophilized

The predicted molecular weight of Recombinant Human Lymphotactin is Mr 10.4 kDa.

This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH₃CN) and 0.1% trifluoroacetic acid (TFA).

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

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1. Saucedo-Cardenas, O. et al. (2009) Biotechnol. Lett. 31: 215
2. McGhee, JR. et al. (1999) J. Immunol. 162: 1959