Myostatin propeptide (MRPO) has a very high binding affinity to myostatin and is a natural inhibitor of myostatin. MPRO is considered an attractive strategy for the treatment of muscle-wasting diseases such as muscular dystrophies.1 Disruption of myostatin function by its propeptide, shifts dietary fat utilization toward muscle tissues with minimal effects on adiposity, therefore, enhancing muscle growth by myostatin propeptide during the early developmental stage. It may also serve as an effective means for obesity prevention.2
>98% by SDS Page
Data not yet available.
Protein Accession No.
Predicted Molecular Mass
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
References & Citations
1. Xiao X. et al. (2008) Hum Gene Ther. 19: 241 2. Baoping Z. et al. (2006) Molec. Reprod. Development 73: 462
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.