Recombinant Human Myostatin

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Pricing & Details

Product. No.M1100
Alternate Names
Growth Differentiation Factor 8 (GDF8)
Expression Host
E. coli
Species
Human
Prod No.
Size
Price
Avail.
Qty
Add to cart
M1100-10 µg
10 µg
$224.00
In stock
Max:
Min: 1
Step: 1
M1100-100 µg
100 µg
$788.00
In stock
Max:
Min: 1
Step: 1
M1100-500 µg
500 µg
$3,456.00
In stock
Max:
Min: 1
Step: 1
M1100-1 mg
1 mg
$5,704.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Background

Myostatin (Mstn)is a secreted growth and differentiating factor (GDF-8) that belongs to the transforming growth factor-beta (TGF-beta) superfamily.1 It is expressed specifically in developing and mature skeletal muscle and appears to act as a negative regulator of muscle development.2 Myostatin plays a significant, direct role in bone formation and regeneration.3

Protein Details

Purity
>95% by SDS Page and HPLC
Endotoxin Level
<1.0 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human Myostatin was determined by the inhibition of the prolifiration of MPC-11 cells. The expected ED50 is < 20 ng/ml.
Expression Host
E. coli
Protein Accession No.
O14793(267-375)
Amino Acid Sequence
DFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS
State of Matter
Lyophilized
Predicted Molecular Mass
The molecular weight of Recombinant Human Myostatin is Mr 25 kDa.
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Bass, JJ. et al. (1999) J Cell Physiol. 180: 1
2. Smith, TP. et al. (2001) Anim. Genet. 29: 19
3. Hamrick, MW. et al. (2009) Bone 44: 17
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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