Recombinant Human Relaxin-3

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Pricing & Details

Product. No.R100
Alternate Names
ZINS4, RXN3, H3, Insulin 7 (INSL-7)
Expression Host
E. coli
Species
Human
Prod No.
Size
Price
Avail.
Qty
Add to cart
R100-25 µg
25 µg
$249.00
In stock
Max:
Min: 1
Step: 1

Background

Relaxin-3 (RNL3) is one of the 7 peptides of Relaxin which is an insulin-related peptide hormone.1 Relaxin 3 is expressed in neurons of the brain stem that inneravate wide areas of the forebrain. Relaxin 3 mRNA levels in these neurons are increased in response to restraint stress, and by central administration of corticotropin-releasing factor (CRF).2 Relaxin-3 may act as a central signal linking nutritional status and reproductive function.3

Protein Details

Purity
>95% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
dvlaglsssc ckwgcsksei sslc (A chain) & aapygvrlcg refiravift cggsrwr (B chain)
N-terminal Sequence Analysis
Asp119 (A chain) & Ala27 (B chain)
State of Matter
Lyophilized
Predicted Molecular Mass
This protein consists of a disulfide-linked heterodimer. The predicted molecular weight of Recombinant Human Relaxin-3 is Mr A Chain-2.46, B Chain-3.04 kDa.
Formulation
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Kane, JF. et al. (2008) Protein Expr Purif. 60: 110
2. Yoshimoto, K. et al. (2009) J Neurosci Res. 87: 820
3. Bloom, SR. et al. (2008) Am J Physiol Endocrinol Metab 295: E278
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Description
R1292
R100
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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