Recombinant Human TGF-β2 (Mammalian Derived)

Recombinant Human TGF-β2 (Mammalian Derived)

Product No.: T226

[product_table name="All Top" skus="T226"]

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Alternate Names
Transforming Growth Factor Beta 2 [Mammalian Derived], Glioblastoma-Derived T-Cell Suppressor Factor, G-TSF, BSC-1 Cell Growth Inhibitor, Polyergin, Cetermin
Product Type
Recombinant Protein
Expression Host
NS0 Cells
Species
Human

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Data

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Background

Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a potent cytokine that modulates embryonic development, bone formation, mammary development, wound healing, hematopoiesis, cell cycle progression and the production of the extracellular matrix.

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human Transforming Growth Factor Beta 2 is determined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The ED<sub>50</sub> was found to be 5 x 10<sup>6</sup> units/mg.
Protein Accession No.
Amino Acid Sequence
Ala303-Ser414
N-terminal Sequence Analysis
Ala303
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human TGF-β2 is Mr 12.7 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is 12 kDa (reducing conditions) and 24 kDa (non-reducing conditions).
Predicted Molecular Mass
12.7
Formulation
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.