Recombinant Human TrkC

Recombinant Human TrkC

Product No.: T391

[product_table name="All Top" skus="T391"]

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Alternate Names
Tropomyosin-Related Kinase C, NTRK3, GP145
Product Type
Recombinant Protein
Expression Host
NS0 Cells
Species
Human

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Background

Tropomyosin-related kinase C (TrkC) is a receptor for neurotrophins, a family of closely related proteins that are important physiological regulators of the survival of specific neurons within the peripheral nervous system (PNS) of vertebrates.1 TrkC specifically mediates biological responses to neurotrophin-3.2

Protein Details

Purity
>95% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Fusion Protein Tag
Fc Fusion Protein
Protein Accession No.
Amino Acid Sequence
cpancvcsk teincrrpdd gnlfpllegq dsgnsngnas initdisrni tsihienwrs lhtlnavdme lytglqklti knsglrsiqp rafaknphlr yinlssnrlt tlswqlfqtl slrelqleqn ffncscdirw mqlwqeqgea klnsqnlyci nadgsqlplf rmnisqcdlp eisvshvnlt vregdnavit cngsgsplpd vdwivtglqs inthqtnlnw tnvhainltl vnvtsedngf tltciaenvv gmsnasvalt vyypprvvsl eepelrlehc iefvvrgnpp ptlhwlhngq plreskiihv eyyqegeise gcllfnkpth ynngnytlia knplgtanqt inghflkepf pestdnfilf devsptppit vthkpeeddi egrmdpkscd kthtcppcpa pellggpsvf lfppkpkdtl misrtpevtc vvvdvshedp evkfnwyvdg vevhnaktkp reeqynstyr vvsvltvlhq dwlngkeykc kvsnkalpap iektiskakg qprepqvytl ppsrdeltkn qvsltclvkg fypsdiavew esngqpenny kttppvldsd gsfflysklt vdksrwqqgn vfscsvmhea lhnhytqksl slspgkhhhh hh
N-terminal Sequence Analysis
Cys32
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human TrkC is Mr 72 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 130-150 kDa.
Predicted Molecular Mass
72
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Klein, R. et al. (1996) Genes Dev. 10: 2849
2. Bloch, B. et al. (1994) Neuroscience 61: 245

Certificate of Analysis

IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
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Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.