Recombinant Mouse EDAR
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BackgroundEctodysplasin A receptor, also known as EDAR is a cell surface receptor of the tumor necrosis factor receptor (TNFR) family involved in the development of hair follicles, teeth, and sweat glands. 1 EDAR is the genetic determinant of hair thickness as well as a strong contributor to hair fiber thickness variation among Asian populations. 2 Protein DetailsPurity >90% by SDS-PAGE and analyzed by silver stain. Endotoxin Level <0.1 EU/µg as determined by the LAL method ⋅ <1.0 EU/µg as determined by the LAL method Fusion Protein Tag Fc Fusion Protein Protein Accession No. Amino Acid Sequence edsn cgeneyhnqt tglcqqcppc rpgeepymsc gygtkdddyg cvpcpaekfs kggyqicrrh kdcegffrat vltpgdmend aecgpclpgy ymlenrprni ygmvcyscll appntkecvg atsgvsahss stsggstlsp fqhahkelsg qghlatalid iegrmdpksc dkthtcppcp apellggpsv flfppkpkdt lmisrtpevt cvvvdvshed pevkfnwyvd gvevhnaktk preeqynsty rvvsvltvlh qdwlngkeyk ckvsnkalpa piektiskak gqprepqvyt lppsrdeltk nqvsltclvk gfypsdiave wesngqpenn ykttppvlds dgsfflyskl tvdksrwqqg nvfscsvmhe alhnhytqks lslspgk N-terminal Sequence Analysis Glu27 State of Matter Lyophilized Predicted Molecular Mass The predicted molecular weight of Recombinant Mouse EDAR is Mr 44.3 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 55-60 kDa. Predicted Molecular Mass 44.3 Formulation This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives. Storage and Stability This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. Country of Origin USA Shipping Next Day Ambient NCBI Gene Bank References & Citations1. Headon, DJ. et al. (2008)Hum Genet. 29:1405 2. Tokunaga, K et al. (2008)Hum Genet. 124:179 Technical ProtocolsCertificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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