Recombinant Mouse FGF-Basic

Recombinant Mouse FGF-Basic

Product No.: F1022

[product_table name="All Top" skus="F1022"]

- -
- -
Alternate Names
Fibroblast Growth Factor-Basic, B-FGF, FGF-2, FGF-β, FGFB, Prostatropin, NUDT6
Product Type
Recombinant Protein
Expression Host
E. coli Cells
Species
Mouse

- -
- -
Select Product Size

Data

- -
- -

Background

Acidic and basic fibroblast growth factors (FGFs) are members of a family of proteins that exert pleiotropic effects in a range of cell types including skeletal myocytes.1 Fibroblast growth factor basic (FGF basic) significantly promote angiogenesis; a central event for the growth and metastasis of solid tumors.2 It is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, placenta, and monocytes, epithelial and endothelial cells. FGF-basic plays a central role during prenatal development and postnatal growth and regeneration of tissues, by promoting cellular proliferation and differentiation. FGF-basic is one of the angiogenesis factors and may promote wound healing.3

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Protein Accession No.
Amino Acid Sequence
alpedggaaf ppghfkdpkr lycknggffl rihpdgrvdg vreksdphvk lqlqaeergv vsikgvcanr ylamkedgrl laskcvteec ffferlesnn yntyrsrkys swyvalkrtg qyklgsktgp gqkailflpm saks
N-terminal Sequence Analysis
Ala11
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse FGF-b is Mr 16.2 kDa.
Predicted Molecular Mass
16.2
Formulation
This recombinant protein was lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Swain, JL. et al. (1991) Developement 111: 741
2. Grevers, G. et al. (1997) Laryngorhinootologie 76: 421
3. Bühring, HJ. et al. (2007) Differentiation. 75(4):279-91
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
- -
- -
Products are for research use only. Not for use in diagnostic or therapeutic procedures.