Recombinant Mouse IL-17E

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Pricing & Details

Product. No.I-850
Alternate Names
IL-25
Expression Host
E. coli
Species
Mouse
Prod No.
Size
Price
Avail.
Qty
Add to cart
I-850-25 µg
25 µg
$224.00
In stock
Max:
Min: 1
Step: 1
I-850-100 µg
100 µg
$512.00
In stock
Max:
Min: 1
Step: 1
I-850-500 µg
500 µg
$1,949.00
In stock
Max:
Min: 1
Step: 1
I-850-1 mg
1 mg
$3,214.00
In stock
Max:
Min: 1
Step: 1

Background

IL-17E, also known as IL-25, is a novel member of the IL-17 family of cytokines1 and a unique pleiotropic cytokine and may be an important mediator of inflammatory and immune responses.2 IL-17E has a heterodimeric receptor. The receptor is composed of two subunits IL-17RA and IL-17RB. Although IL-17E only binds IL-17RB directly, both subunit receptors are essential for IL-17E functions. IL-17E induces activation of NF-κB and stimulates production of the proinflammatory chemokine IL-8. 1 IL-17E may contribute to the induction and maintenance of eosinophilic inflammation in the airways by acting on lung fibroblasts and therefore has a role in asthma pathophysiology.3

Protein Details

Purity
>95% by SDS-PAGE and HPLC
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Expression Host
E. coli
Protein Accession No.
State of Matter
Lyophilized
Predicted Molecular Mass
The molecular weight of Recombinant Mouse IL-17E is Mr 35.5 kDa.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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