Recombinant Mouse MIP-1γ

Macrophage inflammatory protein 1 gamma (MIP-1 gamma) is a monokine with inflammatory, pyrogenic, and chemokinetic CC properties. MIP-1 gamma plays an important role in the differentiation and survival of osteoclasts.¹

The biological activity of Mouse MIP-1γ was determined by its ability to chemoattract mouse BaF/3 cells transfected with hCCR-1 and by its ability to chemoattract human THP-1 cells. The expected ED₅₀ for these effects are typically 0.002 - 0.01 μg/ml and 0.2 - 0.6 μg/ml, respectively.

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Gln22

Lyophilized

The predicted molecular weight of Recombinant Mouse MIP-1γ is Mr 11.5 kDa.

11.5

This recombinant protein was lyophilized from a 0.2 μm filtered solution in 35% acetonitrile (CH₃CN) and 0.1% trifluoroacetic acid (TFA).

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

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1. Stashenko, P.et al. (2004) J. Immunol. 173: 2084