BackgroundResistin-Like Molecule Beta (RELMβ) is a novel class of cysteine-rich proteins secreted into the circulation implicated in hepatic insulin resistance and inflammation. RELMβ is specifically produced by intestinal goblet cells1 and can be found in high quantities in stool. RELMβ may be involved in the development of scleroderma-associated pulmonary hypertension.2 Protein DetailsPurity >95% by SDS Page and HPLC Endotoxin Level <0.1 EU/µg as determined by the LAL method Expression Host E. coli Protein Accession No. Q99P86 Amino Acid Sequence MQCSFESLVD QRIKEALSRQ EPKTISCTSV TSSGRLASCP AGMVVTGCAC GYGCGSWDIR NGNTCHCQCS VMDWASARCC RMA State of Matter Lyophilized Predicted Molecular Mass The predicted molecular weight of Recombinant Mouse RELMβ is Mr 18 kDa. Formulation This recombinant protein was lyophilized from a 0.2 μm filtered solution in 0.1% trifluoroacetic acid (TFA). Storage and Stability The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient PubMed References & Citations1. Marie JC et al. (2008) Inflamm Bowel Dis. 14: 931
2. Johns RA et al. (2009) Am J Respir Cell Mol Biol. 87: 820
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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