Recombinant Mouse RELMα

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Pricing & Details

Product. No.R1140
Alternate Names
Cysteine-Rich Secreted Protein FIZZ1
Expression Host
E. coli
Species
Mouse
Prod No.
Size
Price
Avail.
Qty
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R1140-25 µg
25 µg
$224.00
In stock
Max:
Min: 1
Step: 1
R1140-100 µg
100 µg
$512.00
In stock
Max:
Min: 1
Step: 1
R1140-500 µg
500 µg
$1,949.00
In stock
Max:
Min: 1
Step: 1
R1140-1 mg
1 mg
$3,214.00
In stock
Max:
Min: 1
Step: 1

Background

RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha re still unknown. Recombinant mouse RELM-alpha is a 10.0 kDa monomeric protein containing 88 amino acid residues.

Protein Details

Purity
>97% by SDS Page and HPLC
Endotoxin Level
<1.0 EU/µg
Biological Activity
Data not yet available.
Expression Host
E. coli
Protein Accession No.
Q9EP95
Amino Acid Sequence
MDETIEIIVE NKVKELLANP ANYPSTVTKT LSCTSVKTMN RWASCPAGMT ATGCACGFAC GSWEIQSGDT CNCLCLLVDW TTARCCQLS
State of Matter
Lyophilized
Predicted Molecular Mass
The molecular weight of Recombinant Mouse RELMα is Mr 13.3 kDa.
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.5 with no calcium, magnesium, or preservatives.
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed

References & Citations

1. Bowman, MR. et al. (2010) Eur Respir J. 36(5):1165-73. Article Link
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Prod No.
Description
R1140
R1151
Products are for research use only. Not for use in diagnostic or therapeutic procedures.