Recombinant Mouse VEGF R1

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Pricing & Details

Product. No.V122
Alternate Names
Vascular Endothelial Growth Factor Receptor 1, FLT1, FLT, Vascular Permeability Factor Receptor, Tyrosine-Protein Kinase Receptor FLT, Tyrosine-Protein Kinase FRT, Fms-Like Tyrosine Kinase 1, FRT
Expression Host
NS0 cells
Species
Mouse
Prod No.
Size
Price
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V122-100 µg
100 µg
$409.00
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Min: 1
Step: 1

Background

Vascular endothelial growth factor receptor 1 (VEGF R1), also known as FLT1, is an essential receptor tyrosine kinase that regulates mammalian vascular development and embryogenesis.1 VEGFR1 is mainly expressed in vascular endothelial cells but also in peripheral blood monocytes. VEGFR1 signaling promotes lymphangiogenesis as well as angiogenesis mainly by increasing bone marrow–derived macrophage recruitment.2

Protein Details

Purity
>90% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Fusion Protein Tag
Fc Fusion Protein
Expression Host
NS0 cells
Protein Accession No.
Amino Acid Sequence
sklk vpelslkgtq hvmqagqtlf lkcrgeaahs wslpttvsqe dkrlsitpps acgrdnrqfc stltldtaqa nhtglytcry lptstskkkk aessiyifvs dagspfiemh tdipklvhmt egrqliipcr vtspnvtvtl kkfpfdtltp dgqritwdsr rgfiianaty keigllncea tvnghlyqtn ylthrqtnti ldvqirppsp vrllhgqtlv lnctatteln trvqmswnyp gkatkrasir qridrshshn nvfhsvlkin nvesrdkgly tcrvksgssf qsfntsvhvy ekgfisvkhr kqpvqettag rrsyrlsmkv kafpspeivw lkdgspatlk sarylvhgys liikdvtted agdytillgi kqsrlfknlt atlivnvkpq iyeksvsslp spplyplgsr qvltctvygi prptitwlwh pchhnhsker ydfctenees fildpssnlg nriesisqrm tviegtnktv stlvvadsqt pgiyscrafn kigtvernik fyvtdvpngf hvslekmpae gedlklscvv nkflyrditw illrtvnnrt mhhsiskqkm attqdysitl nlviknvsle dsgtyacrar niytgedilr ktevlvrdse aphllqnlsd yevsisgstt ldcqargvpa pqitwfknnh kiqqepgiil gpgnstlfie rvteedegvy rcratnqkga vesaayltvq gtsdksnlei egrmdpkscd kthtcppcpa pellggpsvf lfppkpkdtl misrtpevtc vvvdvshedp evkfnwyvdg vevhnaktkp reeqynstyr vvsvltvlhq dwlngkeykc kvsnkalpap iektiskakg qprepqvytl ppsrdeltkn qvsltclvkg fypsdiavew esngqpenny kttppvldsd gsfflysklt vdksrwqqgn vfscsvmhea lhnhytqksl slspgkhhhh hh
N-terminal Sequence Analysis
Ser27
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse VEGF R1 is Mr 110 kDa. However, the actual molecular weight as observed by migration on SDS-PAGE is Mr 150-170 kDa.
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from a solution of 20mM MOPS, 500 mM NaCl and 0.05% CHAPS, pH 7.0.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Ponnambalam, S. et al. (2009) Exp Cell Res. 315(5):877-89.
2. Shibuya, M. et al. (2008) Arteriosclerosis, Thrombosis, and Vascular Biol. 28: 658
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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