TACI Blocking Peptide

This peptide sequence is located at amino acids 2 to 16 of Human TACI protein.

This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.

Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

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Transmembrane activator & calcium modulator and cyclophilin ligand (CAML) interactor (TACI) is lymphocyte specific member^1,2 of the tumor necrosis factor-receptor superfamily³ and is expressed in B-lymphocytes and may act to regulate humoral immunity.⁴ TACI also serves as a receptor for B-cell activating factor of the TNF family (BAFF) and as a proliferation-inducing ligand (APRIL).⁵

1. Schwaller J et al. (2007) Blood 109: 331 2. Slazer U et al. (2005) Nat Genet. 37: 820 3. Bonilla FA et al. (2006) Curr Allergy Asthma Rep. 6: 357 4. Bram RJ et al. (2000) Mamm Genome. 11: 628 5. Kobata T et al. (2007) Blood 109: 2961