TRAIL (CT) Blocking Peptide
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Antibody DetailsProduct DetailsReactive Species Human Product Concentration 0.2 mg/ml Amino Acid Location This peptide sequence is located at amino acids 261 to 277 of Human TRAIL protein. Formulation This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Storage and Handling Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionBackground TNF-related apoptosis-inducing ligand (TRAIL) belongs to the tumor necrosis factor family and activates rapid apoptosis in tumor cells, and binds to the death-signaling receptor DR4.1 TRAIL is a potential tumor specific cancer therapeutic agent, since it selectively induces apoptosis in transformed versus normal cells.2 References & Citations1. Ashkenazi A et al. (1997) Science 227: 818
2. Romeo G et al. (2005) Current Pharmaceutical Design 11: 933 |
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