TRAIL R3 (Extracellular Domain – 2) Blocking Peptide
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Antibody DetailsProduct DetailsReactive Species Human Product Concentration 0.2 mg/ml Amino Acid Location This peptide sequence is located at amino acids 111 to 123 of Human DcR1 protein. Formulation This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Storage and Handling Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. Background TNF-related apoptosis-inducing ligand receptor 3 (TRAIL R3) is an antagonist decoy receptor1 that can inhibit TRAIL-induced apoptosis.2 TRAIL R3 is a plasma membrane-bound protein capable of high affinity interaction with the TRAIL ligand.3 Antigen DetailsReferences & Citations1. Fornace AJ Jr. et al. (1999) Oncogene 18: 4153
2. Büchler MW et al. (2001) Anticancer Res. 21: 3153
3. Smith CA et al. (1997) J Exp Med. 186: 1165
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
