XIAP (CT) Blocking Peptide
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Antibody DetailsProduct DetailsReactive Species Human Product Concentration 0.2 mg/ml Amino Acid Location 13 amino acids near the carboxy-terminus of human XIAP. Formulation This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Storage and Handling Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionBackground X-linked Inhibitor of Apoptosis Protein (XIAP) is a member of a novel family of Inhibitor of Apoptosis (IAP) proteins.1 XIAP is the best characterized and the most potent direct endogenous caspase inhibitor and is considered a key actor in the control of apoptotic threshold in cancer cells.2 XIAP may be considered as a new independent prognostic marker for early recurrence of non-muscular invasive bladder cancer.3 References & Citations1. Chow T et al. (2000) Oncogene 19: 4174
2. Barillé-Nion S et al. (2009) Haematologica 94: 87
3. Na Yan-Qun et al. (2007) Chinese Medical Journal 120: 469 |
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