SARS-CoV-2 Recombinant Proteins
Leinco Technologies understand the importance of quality recombinant proteins and enzymes that produce consistent results for studying COVID-19 and other related diseases. These proteins are vitally important for both vaccine development and diagnostic tests. With over 25 years of experience, Leinco’s SARS-CoV-2 recombinant proteins are produced with > 95% purity level by SDS page, an endotoxin of ≤ 1.0 EU/mg, and contain no carrier protein.
The angiotensin-converting enzyme 2 (ACE2) is the host portal for SARS-CoV-2 entry into cells1. The trimeric spike (S) protein of SARS-CoV-2 is primed by TMPRSS2 and consists of the S1 and S2 domains1. The S1 subunit contains the N-terminal domain (NTD) and the receptor-binding domain (RBD), encoded by all coronaviruses. In addition, the Nucleocapsid (N) Protein is the most abundant protein for coronavirus binding to the RNA genome. The N protein plays a role in transcription, replication, and packaging of the viral RNA genome, while also affecting host cell responses such as cell cycle and translation2.
SARS-CoV-2 S protein, RBD-Fc tag Coming soon.