Anti-Clozapine – (Clone CLO-1256)
Anti-Clozapine – (Clone CLO-1256)
Product No.: C550
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Clone CLO-1256 Target Clozapine Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Isotype Mouse IgG1 κ Applications ELISA , Lateral Flow |
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Antibody DetailsProduct DetailsHost Species Mouse Immunogen Clozapine-BSA Product Concentration ≥1.0 mg/ml Purity >90% for SDS PAGE Formulation Formulated in 0.015M potassium phosphate buffered saline (0.85%), pH 7.2 and contains 0.05% sodium azide. State of Matter Liquid Product Preparation This monoclonal antibody is purified by ion exchange chromatography. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2 – 8° C Wet Ice Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Anti-Clozapine (clone CLO-1256) is specific for clozapine. Background Clozapine, a unique atypical antipsychotic, is primarily employed in the treatment of
schizophrenia, particularly in cases resistant to other antipsychotic medications.
Introduced in the 1970s, clozapine stands out due to its distinct mechanism of action,
primarily antagonizing dopamine receptors, but also influencing other neurotransmitter
systems, including serotonin, histamine, and adrenergic receptors. This broad-spectrum
modulation contributes to its efficacy in managing symptoms. Notably, clozapine is
associated with a risk of agranulocytosis, a potentially life-threatening reduction in white
blood cell count. Due to this risk, regular blood monitoring, specifically complete blood
cell counts, is crucial for individuals on clozapine therapy. These diagnostic tests are
essential for detecting early signs of agranulocytosis, allowing for prompt intervention
and ensuring the overall safety and effectiveness of clozapine treatment in patients with
severe or treatment-resistant schizophrenia. Antigen DetailsResearch Area Matched Pair . IVD Raw Material . Psychiatric References & CitationsHaidary HA, Padhy RK. Clozapine. Treasure Island (FL): StatPearls Publishing; 2024 Jan. Link Text Technical Protocols Lateral Flow |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
