Anti-FAK (Phospho-Tyr861) Antibody (43059)
Data
Immunoblotting: Detection of FAK in extracts of HT29 cells untreated or treated with EGF. - -
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Antibody DetailsProduct DetailsReactivity Species Human Host Species Rabbit Immunogen Peptide sequence that includes phosphorylation site of tyrosine 861 (H-I-Y(p)-Q-P) derived from human FAK. Product Concentration 1.0 mg/ml Formulation PBS (without Mg2 and Ca2 ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. State of Matter Liquid Product Preparation Affinity-purified on phosphopeptide; non-phosphopeptidereactive antibodies were removed by chromatography on non-phosphorylated peptide Storage and Handling This antibody is stable for at least one (1) year at -20°C. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunoblotting: use at dilution of 1:500-1:1,000. A band of ~125kDa is detected.
These are recommended working dilutions. End user should determine optimal dilutions for their applications. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Polyclonal Antibody specific to FAK (Phospho-Tyr861) Background Focal Adhesion Kinase, FAK (also known as PTK2 protein tyrosine kinase 2, PTK2) is a protein that, in humans, is encoded by the PTK2 gene. FAK is a focal adhesion-associated protein kinase involved in cellular adhesion and spreading processes. It has been shown that when FAK is blocked, breast cancer cells become less metastatic due to decreased mobility. Antigen DetailsUniProt.org Research Area Phosphospecific Antibodies References & CitationsTechnical Protocols |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
