Anti-Human Apoptosis Related Protein (NT) (ARTS)

Home/Primary Monoclonal Antibodies/Apoptosis & Cell Biology/Anti-Human Apoptosis Related Protein (NT) (ARTS)

Pricing & Details

Product No.A191
Protein
ARTS
Formats AvailableView All
Product Type
Polyclonal Antibody
Alternate Names
Septin 4, PNUTL2
Applications
IHC FFPE
,
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
A191-20 µg
20 µg
$95.00
In stock
Max:
Min: 1
Step: 1
A191-0.1 mg
0.1 mg
$440.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Data

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Immunogen
PN:A192
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human ARTS recognizes an epitope near the N-terminus of Human ARTS. This polyclonal antibody was purified using affinity chromatography.
Background
Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-b signaling pathway (1). ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene (1-4) is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-b and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.

Antigen Details

Protein
PubMed

References & Citations

1. Larisch, S. et al. (2000) Nat Cell Biol 2(12):915
2. Depraetere, V. (2000) Nat Cell Biol. 2(12):E219
3. Paavola, P. et al. (1999) Genomics 55(1):122
4. Zieger, B. et al. (2000) Gene 261(2):197
IHC
General Western Blot Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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