Anti-Human APRIL (Extracellular Domain-2)
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Antibody DetailsProduct DetailsReactive Species Human Host Species Rabbit Immunogen PN:A186 Product Concentration 0.5 mg/ml Formulation This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. Storage and Handling This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient RRIDAB_2828052 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Anti-Human APRIL recognizes an epitope in the extracellular domain of Human and Mouse APRIL. This polyclonal antibody was purified using affinity chromatography. Background A proliferation-inducing ligand (APRIL) is a TNF-like cytokine that stimulates tumor cell growth.1 It is of low abundance in normal tissues.2 APRIL acts as a proliferative factor in megakaryocytopoiesis, a developmental hematopoietic process responsible for progenitor cell differentiation to megakaryoblasts and megakaryocytes, leading to platelet formation.3 APRIL may be implicated in the regulation of tumor cell growth.2 Antigen DetailsNCBI Gene Bank ID References & Citations1. Sarah G. Hymowitz et al. (2004) J Mol Biol. 343: 283
2. (1998) Jürg Tschopp
3. Ruggero De Maria et al. (2004) Blood 104: 3169
Technical ProtocolsIHC FFPE  |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
