Anti-Human Bonzo (CT)

Anti-Human Bonzo (CT)

Product No.: B360

[product_table name="All Top" skus="B360"]

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Target
Bonzo
Product Type
Polyclonal Antibody
Alternate Names
STRL33, TYMSTR
Applications
WB

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human BONZO recognizes an epitope near the C-terminus of Human Bonzo. This polyclonal antibody was purified using affinity chromatography.
Background
Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor. Bonzo/STRL33 is used by SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.

Antigen Details

PubMed
NCBI Gene Bank ID

References & Citations

1. Deng, H. K. et al. (1997) Nature 388:296 2. Liao, F. et al. (1997) J. Exp. Med. 185:2015 3. Alkhatib, G. et al. (1997) Nature 388:238 4. Loetscher, M. et al. (1997) Curr. Biol. 7:652
General Western Blot Protocol
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.