Anti-Human CARD9

Product No.: C1143

[product_table name="All Top" skus="C1143"]

- -
- -
Target
CARD9
Product Type
Polyclonal Antibody
Alternate Names
Caspase Recruitment Domain Family Member 9
Applications
WB

- -
- -
Select Product Size

Data

C1143 Western Blot
C1143 IHC CARD9
- -
- -

Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:C1144
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
Rabbit Anti-Human Caspase Recruitment Domain Family Member 9 (CARD9) recognizes Human CARD9. This polyclonal antibody was purified using affinity chromatography.
Background
Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10.1 CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-κB. CARD9 is an upstream activator of BCL-10 and NF-κB signaling.

References & Citations

1. Bertin, J. et al (2000) J Biol Chem. 275(52):41082-6.
General Western Blot Protocol

Certificate of Analysis

- -
- -
Prod No.
Description
C1143
C1144
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.