Anti-Human Caspase-13

Anti-Human Caspase-13

Product No.: C1117

[product_table name="All Top" skus="C1117"]

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Target
Caspase-13
Product Type
Polyclonal Antibody
Alternate Names
ERICE
Applications
IHC FFPE
,
WB

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:C1129
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human Caspase-13 recognizes mouse, rat and human Caspase-13. This polyclonal antibody was purified using affinity chromatography.
Background
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 b Converting Enzyme) and caspase-13.1 Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.1

Antigen Details

References & Citations

1. Humke, EW. et al. (1998) J Biol Chem 273:15702-7
IHC FFPE
General Western Blot Protocol
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Prod No.
Description
C1117
Products are for research use only. Not for use in diagnostic or therapeutic procedures.