Anti-Human CD151 – APC

Anti-Human CD151 – APC

Product No.: C2042

[product_table name="All Top" skus="C2042"]

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Clone
50-6
Target
CD151
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
PETA-3, Platelet-Endothelial tetra-span antigen, Tspan-24
Isotype
IgG1
Applications
FC

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Product Concentration
0.1 mg/ml
Formulation
This Allophycocyanin (APC) antibody conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Product Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Storage and Handling
This Allophycocyanin (APC) monoclonal antibody conjugate is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Excitation Laser
Red Laser (633 nm)
Applications and Recommended Usage?
Quality Tested by Leinco
FC For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. Each lot of this antibody is quality control tested
Additional Applications Reported In Literature ?
Additional reported applications (for the relevant formats) include:
Western blotting
Immunocytochemical staining of HEp-3 cells1
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Clone 50-6 recognizes an epitope on human CD151.
Background
CD151 is a 29 kD cell surface glycoprotein that is a member of the transmembrane 4 superfamily (tetraspanin family), which is characterized by cell-surface proteins consisting of four hydrophobic domains that mediate signal transduction events involved in the regulation of cell development, activation, growth and motility. CD151 is known to complex with integrins and other transmembrane 4 superfamily proteins and is involved in cell adhesion, migration, and tumor cell metastasis.
Antigen Distribution
CD151 is found on immature hematopoietic cells, megakaryocytes, platelets, keratinocytes, epithelial cells, muscle cells, Schwann cells, vascular endothelium, and activated T-cells.

Antigen Details

Ligand/Receptor
CD9, CD181, integrins α3β1, α5β1 and α6β4
Function
Cell adhesion, migration
NCBI Gene Bank ID

References & Citations

1. Testa, et. al., Cancer Research. 59:3812-3820, 1999
Flow Cytometry

Certificate of Analysis

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.