Anti-Human CD151 – Purified

Anti-Human CD151 – Purified

Product No.: C2038

[product_table name="All Top" skus="C2038"]

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Clone
50-6
Target
CD151
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
PETA-3, Platelet-Endothelial tetra-span antigen, Tspan-24
Isotype
IgG1
Applications
FC
,
ICC
,
WB

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Product Concentration
0.1 mg/ml
Formulation
This Purified conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
FC The suggested concentration for this 50-6 antibody for staining cells in flow cytometry is ≤ 1 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Additional Applications Reported In Literature ?
ICC
WB
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Clone 50-6 recognizes an epitope on human CD151.
Background
CD151 is a 29 kD cell surface glycoprotein that is a member of the transmembrane 4 superfamily (tetraspanin family), which is characterized by cell-surface proteins consisting of four hydrophobic domains that mediate signal transduction events involved in the regulation of cell development, activation, growth and motility. CD151 is known to complex with integrins and other transmembrane 4 superfamily proteins and is involved in cell adhesion, migration, and tumor cell metastasis.
Antigen Distribution
CD151 is found on immature hematopoietic cells, megakaryocytes, platelets, keratinocytes, epithelial cells, muscle cells, Schwann cells, vascular endothelium, and activated T-cells.

Antigen Details

Ligand/Receptor
CD9, CD181, integrins α3β1, α5β1 and α6β4
NCBI Gene Bank ID

References & Citations

1. Testa, et. al., Cancer Research. 59:3812-3820, 1999
Flow Cytometry
ICC
General Western Blot Protocol

Certificate of Analysis

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.