Anti-Human CD61 (Integrin β3) [F11] – PE

This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.

This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.

Next Day 2-8°C

Blue Laser (488 nm) and/or Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Mouse Anti-Human CD61 (Clone F11) recognizes Human CD61. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Anti-CD61 recognizes the (Mr 110 kDa) common ß-subunit of the gp IIb/IIIa complex and the vitronectin receptor (VNR). The gp IIb (CD41) antigen and the gp IIIa (CD61) antigen form the cell adhesion complex (gp IIb/IIIa) which is the receptor on platelets for fibrinogen, von Willebrand factor, fibronectin and vitronectin.

Anti-CD61 can be used to identify platelets and megakaryocytes. It may also be used to characterize leukemias and in studies of cell adhesion molecules.

The CD61 antigen is present on virtually all resting and activated platelets. The antigen is also known to be present on endothelial cells, megakaryocytes and some leukemias of myeloid, erythroid and lymphoid origin.

Fibronectin, vitronectin, vWF

1. Helfrich, M. N. et al. submitted for publication Phycobilliproteins are protected under the following patents: (U.S. patents No. 4,520,110 and 4,542,104, European patent no. 76695, Canadian patent No. 1,179,942 and Australian patent No. 548,440).