Anti-Human CD61 (Integrin β3) [F11] – Purified
Anti-Human CD61 (Integrin β3) [F11] – Purified
Product No.: C191
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Clone F11 Target CD61 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names Integrin β3, Glycoprotein IIIa Isotype IgG1 Applications FC |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Product Concentration 0.5 mg/ml Formulation This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day Ambient RRIDAB_2828988 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for this F11 antibody for staining cells in flow cytometry is ≤ 1 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Mouse Anti-Human CD61 (Clone F11) recognizes Human CD61. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Anti-CD61 recognizes the (Mr 110 kDa) common ß-subunit of the gp IIb/IIIa complex and the vitronectin receptor (VNR). The gp IIb (CD41) antigen and the gp IIIa (CD61) antigen form the cell adhesion complex (gp IIb/IIIa) which is the receptor on platelets for fibrinogen, von Willebrand factor, fibronectin and vitronectin. Background Anti-CD61 can be used to identify platelets and megakaryocytes. It may also be used to characterize leukemias and in studies of cell adhesion molecules. Antigen Distribution The CD61 antigen is present on virtually all resting and activated platelets. The antigen is also known to be present on endothelial cells, megakaryocytes and some leukemias of myeloid, erythroid and lymphoid origin. Ligand/Receptor Fibronectin, vitronectin, vWF PubMed NCBI Gene Bank ID UniProt.org Research Area Immunology References & Citations1. Helfrich, M. N. et al. submitted for publication Technical Protocols Certificate of Analysis |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
