Anti-Human CD61 (Integrin β3) (Clone F11) – Purified

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Pricing & Details

Product No.C191
Clone
F11
Protein
CD61
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Integrin β3, Glycoprotein IIIa
Isotype
Mouse
IgG1
Applications
FC
Prod No.
Size
Price
Avail.
Qty
Add to cart
C191-50 µg
50 µg
$55.00
In stock
Max:
Min: 1
Step: 1
C191-100 µg
100 µg
$93.00
In stock
Max:
Min: 1
Step: 1
C191-200 µg
200 µg
$165.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Mouse
Product Concentration
0.5 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day Ambient
Applications and Recommended Usage?
Quality Tested by Leinco
FC The suggested concentration for this F11 antibody for staining cells in flow cytometry is ≤ 1 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-Human CD61 (Clone F11) recognizes Human CD61. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Anti-CD61 recognizes the (Mr 110 kDa) common ß-subunit of the gp IIb/IIIa complex and the vitronectin receptor (VNR). The gp IIb (CD41) antigen and the gp IIIa (CD61) antigen form the cell adhesion complex (gp IIb/IIIa) which is the receptor on platelets for fibrinogen, von Willebrand factor, fibronectin and vitronectin.
Antigen Distribution
The CD61 antigen is present on virtually all resting and activated platelets. The antigen is also known to be present on endothelial cells, megakaryocytes and some leukemias of myeloid, erythroid and lymphoid origin.
Background
Anti-CD61 can be used to identify platelets and megakaryocytes. It may also be used to characterize leukemias and in studies of cell adhesion molecules.

Antigen Details

Protein
Ligand/Receptor
Fibronectin, vitronectin, vWF
PubMed
NCBI Gene Bank ID
Research Area
Immunology

References & Citations

1. Helfrich, M. N. et al. submitted for publication
Flow Cytometry

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.