Anti-Human CTRP1 (Intermediate Domain)

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Pricing & Details

Product No.C1232
Protein
CTPR1
Formats AvailableView All
Product Type
Polyclonal Antibody
Alternate Names
G Protein Coupled Receptor Interacting Protein 1, GIP
Applications
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
C1232-20ug
20 µg
$195.00
In stock
Max:
Min: 1
Step: 1
C1232-0.1 mg
0.1 mg
$397.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Data

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Immunogen
PN:C1258
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human CTPR1 recognizes an epitope in the intermediate domain of Human and Mouse CTPR1. This polyclonal antibody was purified using affinity chromatography.
Background
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7.2 Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues.3 These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene.4 In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.3

Antigen Details

Protein
PubMed

References & Citations

1. Fantuzzi, G. (2005) J. Allergy Clin. Immunol. 115:911
2. Tsao, TS. et al. (2002) Euro. J. Pharmacol. 440:213
3. Wong, GW. et al. (2004) Proc. Natl. Acad. Sci. USA 101:10302
4. Shapiro, L. et al. (1998) Curr. Biol. 8:335
General Western Blot Protocol
Prod No.
Description
C1232
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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