Anti-Human CTRP7 (CT)

Anti-Human CTRP7 (CT)

Product No.: C1254

[product_table name="All Top" skus="C1254"]

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Target
CTRP7
Product Type
Polyclonal Antibody
Applications
IHC FFPE
,
WB

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Data

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:C1296
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human CTRP6 recognizes an epitope near the C-terminus of Human, Mouse and Rat CTRP6. This polyclonal antibody was purified using affinity chromatography.
Background
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7.2 Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues.3 These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene.4 Like the other members of the adiponectin and CTRP protein family, the mature CTRP7 is secreted and can be found in the organism’s circulatory system.1

Antigen Details

PubMed

References & Citations

1. Fantuzzi, G. (2005) J. Allergy Clin. Immunol. 115:911
2. Tsao, TS. et al. (2002) Euro. J. Pharmacol. 440:213
3. Wong, GW. et al. (2004) Proc. Natl. Acad. Sci. USA 101:10302
4. Shapiro, L. et al. (1998) Curr. Biol. 8:335
IHC FFPE
General Western Blot Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.