Anti-Human CX3CR1 (EL)

Pricing & Details

  
Product Type
Polyclonal Antibody
Alternate Names
V28, CMKBRL1
Applications
IHC FFPE
,
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
C1120-0.1 mg
0.1 mg
$355.00
In stock
  

Antibody Details

Reactivity Species
Human
Host Species
Rabbit
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Applications and Recommended Usage ?
(Quality Tested by Leinco)
Western Blotting: To detect Human CX3CR1 this polyclonal antibody can be used at a concentration of 0.5 µg/ml.

Description

Specificity
Rabbit Anti-Human CX3CR1 recognizes an epitope in the extracellular loop of Human CX3CR1. This polyclonal antibody was purified using affinity chromatography.
Background
CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively.1-4 The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.2

Antigen Details

Protein
CX3CR1
PubMed
CX3CR1
NCBI Gene Bank ID

References & Citations

1. Raport, C. J. et al. (1995) Gene 163:295 2. Combadiere, C. et al. (1995) DNA Cell Biol. 14:673 3. Combadiere. C. et al. (1998) Biochem. Biophys. Res. Commun. 253:728 4. Harrison, J. K. et al. (1994) Neurosci. Lett. 169:85
IHC
General Western Blot Protocol
  
Prod No.
Description
C1121
C1120
Products are for research use only. Not for use in diagnostic or therapeutic procedures.