Anti-Human Cytokeratin 19 Antibody (34059)
Anti-Human Cytokeratin 19 Antibody (34059)
Product No.: 34059
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Clone G019.1 Target Cytokeratin 19 Formats AvailableView All Product Type Monoclonal Alternate Names Cytokeratin-19, CK-19, Keratin-19, K19 Isotype Mouse IgG2a Applications IHC |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Recombinant human Cytokeratin 19. Formulation Tris buffer, pH 7.3-7.7, 1% BSA, 0.1% sodium azide. State of Matter Liquid Product Preparation Purified by immunoaffinity chromatography Storage and Handling Store at 2-8°C. Do not freeze. Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Mouse Monoclonal Antibody specific to Cytokeratin 19 Background Cytokeratin19 is the smallest member (40kDa) of the keratin family. It forms intermediate filaments in the intracytoplasmic cytoskeleton of epithelial tissue and provides mechanical support. Cytokeratin 19 is identified in epithelial malignancies such as carcinomas of colon, stomach, pancreas, biliary tract, liver, breast, and thyroid papillary carcinomas. Function Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. {PubMed:16000376}. NCBI Gene Bank ID UniProt.org Research Area Cancer Research References & Citations |
Formats Available
