Anti-Human Cytokeratin 19 Antibody (34059)

Anti-Human Cytokeratin 19 Antibody (34059)

Product No.: 34059

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Clone
G019.1
Target
Cytokeratin 19
Formats AvailableView All
Product Type
Monoclonal
Alternate Names
Cytokeratin-19, CK-19, Keratin-19, K19
Isotype
Mouse IgG2a
Applications
IHC

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Data

Immunohistochemistry: Detection of Cytokeratin 19 in human colon with #34059 diluted 1:100-1:200.
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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Recombinant human Cytokeratin 19.
Formulation
Tris buffer, pH 7.3-7.7, 1% BSA, 0.1% sodium azide.
State of Matter
Liquid
Product Preparation
Purified by immunoaffinity chromatography
Storage and Handling
Store at 2-8°C. Do not freeze.
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco


Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
Mouse Monoclonal Antibody specific to Cytokeratin 19
Background
Cytokeratin19 is the smallest member (40kDa) of the keratin family. It forms intermediate filaments in the intracytoplasmic cytoskeleton of epithelial tissue and provides mechanical support. Cytokeratin 19 is identified in epithelial malignancies such as carcinomas of colon, stomach, pancreas, biliary tract, liver, breast, and thyroid papillary carcinomas.
Function
Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. {PubMed:16000376}.
NCBI Gene Bank ID
UniProt.org
Research Area
Cancer Research

References & Citations

Formats Available

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Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.