Anti-Human G Protein-Coupled Receptor 15 (NT) (GPR15)
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Antibody DetailsProduct DetailsReactive Species Human Host Species Rabbit Product Concentration 0.5 mg/ml Formulation This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. Storage and Handling This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient RRIDAB_2830234 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rabbit Anti-Human G Protein-Coupled Receptor 15 (GPR15) recognizes an epitope near the N-terminus of Human, Mouse and Rat GPR15. This polyclonal antibody was purified using affinity chromatography. Background Human immunodeficiency virus (HIV) and related viruses require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. The genes encoding human and monkey GPR15/BOB (for G protein-coupled receptor 15 and brother of Bonzo, respectively,) were recently cloned. This novel G protein-coupled receptor serves as corecptor for simian immunodeficiency virus (SIV), and for strains of HIV-2 and M-tropic HIV-1. The ligand for GPR15 has not been identified yet. Antigen DetailsNCBI Gene Bank ID UniProt.org References & Citations1. Heiber, M. et al. (1996) Genomics 32:462
2. Deng, H. K. et al. (1997) Nature 388:296
3. Farzan, M. et al. (1997) J. Exp. Med. 186:405 Technical Protocols |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.