Anti-Human GFRα-1 (Intermediate Domain)

Product No.: G576


Target Glial Cell Line-Derived Neurotropic Factor soluble Receptor Alpha 1 Product Type Polyclonal Antibody Alternate Names GFRA1, GDNFR, GDNFRA, GFR-ALPHA-1, MGC23045, RET1L, RETL1, TRNR1 Applications IHC FFPE , WB


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Antibody Details Product Details Reactive Species Human Host Species Rabbit Immunogen PN:G579 Product Concentration 0.5 mg/ml Formulation This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. Storage and Handling This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient RRIDAB_2830235 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. Description Description Specificity Rabbit Anti-Human GDNF Family Receptor Alpha 1 (GFRα-1) recognizes Human GFRα-1. This polyclonal antibody was purified using affinity chromatography. Background GDNF family receptor alpha 1, also known as GFRA1 is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. GFRalpha1 functions as a ligand-induced cell adhesion molecule (LICAM) to establish precise synaptic contacts and induce presynaptic differentiation.¹ PubMed Glial Cell Line-Derived Neurotropic Factor soluble Receptor Alpha 1 NCBI Gene Bank ID 2674 UniProt.org More Information on Uniprot.org References & Citations 1. Ibáñez CF. et al. (2007)Nat Neurosci. 10 : 293 View product citations for antibody PRODUCT_CODE on CiteAb Technical Protocols IHC FFPE Certificate of Analysis Request COA

Antibody Details

Product Details

Reactive Species

Human

Host Species

Rabbit

Immunogen

PN:G579

Product Concentration

0.5 mg/ml

Formulation

This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.

Storage and Handling

This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Country of Origin

USA

Shipping

Next Day Ambient

RRIDAB_2830235

Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity

Rabbit Anti-Human GDNF Family Receptor Alpha 1 (GFRα-1) recognizes Human GFRα-1. This polyclonal antibody was purified using affinity chromatography.

Background

GDNF family receptor alpha 1, also known as GFRA1 is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. GFRalpha1 functions as a ligand-induced cell adhesion molecule (LICAM) to establish precise synaptic contacts and induce presynaptic differentiation.¹

PubMed

Glial Cell Line-Derived Neurotropic Factor soluble Receptor Alpha 1

NCBI Gene Bank ID

2674

UniProt.org

More Information on Uniprot.org