Anti-Human IL-27 (Intermediate Domain)

Anti-Human IL-27 (Intermediate Domain)

Product No.: I-500

[product_table name="All Top" skus="I-500"]

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Target
IL-27
Product Type
Polyclonal Antibody
Alternate Names
Interleukin-27, P28, IL30, IL-27, IL-27p28, IL27
Applications
WB

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:I-512
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human Interleukin-27 (IL-27) recognizes an epitope in the intermediate domain of Human and Mouse IL-27. This polyclonal antibody was purified using affinity chromatography.
Background
Interleukin-27 (IL-27) is a novel IL-12 family member that plays a role in the early regulation of T helper cell 1 initiation, including induction of T-bet and IL-12 receptor beta 2 expression.1 IL-27 is produced by antigen-presenting cells2 and plays an important function in regulating the activity of B and T lymphocytes.3 IL27 may be a potential therapeutic agent against rheumatoid arthritis (RA) at the onset of the disease.4

Antigen Details

PubMed
NCBI Gene Bank ID

References & Citations

1. Yoshimoto T et al. (2004) Cancer Res. 64: 1152 2. De Sauvage FJ et al. (2003) Proceedings of the National Acad of Sci of USA 100: 15047 3. Devergne O et al. (2006) J Immunol. 176: 5890 4. Liew FY et al. (2008) Ann Rheum Dis. 67: 1474
General Western Blot Protocol

Certificate of Analysis

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.